4,4'-二氨基二苯醚：神秘纽带 4,4'-Oxydianiline：The mysterious bond

Introduction

In the world of chemistry, every molecule has its own unique story and purpose. Today, we are going to explore the scientific mystery behind CAS: 101-80-4, a seemingly insignificant chemical number.

Basic Information

4,4'-Diaminodiphenyl ether (4,4'-ODA), with the chemical formula of C12H12N2O and a molecular weight of 200.24, is an important organic compound. 4,4'-Diaminodiphenyl ether has a series of unique physical and chemical properties. It has a high melting point of about 186-187°C and a boiling point greater than 300°C. It is a fine chemical intermediate for the synthesis of medicines, dyes, insulating materials and flame retardant materials. The polyimide resin synthesized from this substance has the characteristics of high thermal stability, low flammability and excellent mechanical properties. As a high molecular weight monomer, 4,4'-Diaminodiphenyl ether has a wide range of applications in chemical industry, medicine, dyes, pigments, pesticides, electricity, electronics and other fields.

Synthesis Route

(1) Using DNDPE as raw material

1. Metal reduction method

2. Alkali sulfide reduction method

3. Hydrazine hydrate reduction method

4. Catalytic hydrogenation reduction method

5. Photocatalytic reduction method

 

(2) Using diphenyl ether as raw material

1. Ammonolysis of dihalogenated diphenyl ether

2. Reduction of dinitrosodiphenyl ether

 

(3) Synthesis of other raw materials

1. 4,4'-diacetyl diphenyl ether as raw material

2. p-Chloroaniline as raw material

3. Hydrogenation reduction of 4-amino-4'-nitrodiphenyl ether

4. Hydroquinone as raw material

 

Application Field

4,4'-Diaminodiphenyl ether has a wide range of applications in many fields due to its unique chemical properties:

 

1. Pharmaceutical industry

In the pharmaceutical field, 4,4'-diaminodiphenyl ether is a key intermediate for the synthesis of a variety of drugs. It can be used to synthesize antihypertensive drugs, antidepressants and some anticancer drugs. During the synthesis of these drugs, the amino and benzene rings in the structure provide the necessary reaction sites, allowing the drug molecules to form specific structures and functions.

2. Material science

4,4'-Diaminodiphenyl ether also has a place in material science. 4,4'-Diaminodiphenyl ether is an important monomer for the synthesis of heat-resistant plastics such as polyimide resin, polymaleimide resin, polyamide-imide resin, polyester-imide resin, epoxy resin and polyurethane. These plastics have excellent heat resistance, mechanical properties and insulation properties, and are widely used in electrical fields such as wind power, high-speed rail transportation, new energy vehicles, transformers and electromagnetic wires, as well as electronic fields such as FCCL, package substrate (COF), and graphite heat dissipation film. 4,4'-Diaminodiphenyl ether can also be used as a crosslinking agent to improve the crosslinking degree and performance of materials.

3. Dye industry

4,4'-Diaminodiphenyl ether is also one of the important raw materials for synthetic dyes. By reacting with different compounds, a series of dyes with different colors and properties can be generated. These dyes are widely used in industries such as textiles, plastics and inks, adding rich colors to our lives.

 

Safety Information

4,4'-Diaminodiphenyl ether should be kept away from strong oxidants. It is toxic. Production equipment should be sealed and the production site should be well ventilated to prevent dust from flying. Operators should wear protective equipment. 4,4'-Diaminodiphenyl ether can cause cancer. Inhalation of vapor or powder or absorption through the skin can cause poisoning. It can damage the human nervous system, cause the blood to form denatured hemoglobin, and has a hemolytic effect.

 

Conclusion

With the advancement of science and technology and the acceleration of industrialization, the market demand for 4,4'-diaminodiphenyl ether continues to grow. Especially in the fields of electrical engineering, electronics, new energy, etc., the application prospects of 4,4'-diaminodiphenyl ether are very broad. In the future, with the continuous innovation of technology and the improvement of the industrial chain, the production cost of 4,4'-diaminodiphenyl ether will be further reduced, the product quality and performance will continue to improve, and the application field will be further expanded.

By deeply understanding its basic information, synthesis process, physical and chemical properties, application fields, and safety information, we can better grasp its market trends and development prospects, and provide strong support for the development of related fields. At the same time, we should also pay attention to its safety and environmental protection issues, strengthen safety protection and environmental protection measures, and ensure its safety and environmental protection during production and use.